[17-JAN-2003] 1 LAMICTAL® PRODUCT INFORMATION 2 (lamotrigine) 3 Tablets 4 5 LAMICTAL® 6 (lamotrigine) 7 Chewable Dispersible Tablets 8 9 10 SERIOUS RASHES REQUIRING HOSPITALIZATION AND DISCONTINUATION Epilepsy. Adjunctive Therapy. Lamictal is indicated as adjunctive therapy for the following seizure types in patients aged 2 years and older: • partial-onset seizures. Dosering Dersom beregnet dose ikke gir et helt antall tabletter, skal administrert dose reduseres til nærmeste hele tablett. Pga. risiko for utslett må startdose og videre anbefalt doseøkning ikke overskrides (se Forsiktighetsregler). Adjunctive Therapy. Lamictal XR is indicated as adjunctive therapy for primary generalized tonic-clonic (PGTC) seizures and partial-onset seizures with or without secondary generalization in patients aged 13 years and older. Discontinuation or Dose Reduction in the KEPPRA XR Controlled Clinical Study. In the controlled clinical study using KEPPRA XR, 5.2% of patients receiving KEPPRA XR and 2.5% receiving placebo discontinued as a result of an adverse reaction. Dosing For Myoclonic Seizures In Patients 12 Years Of Age And Older With Juvenile Myoclonic Epilepsy. Initiate treatment with a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Lamotrigine, sold as the brand name Lamictal among others, is an anticonvulsant medication used to treat epilepsy and bipolar disorder. For epilepsy, this includes focal seizures, tonic-clonic seizures, and seizures in Lennox-Gastaut syndrome. In bipolar disorder, it is used to treat acute episodes of depression, rapid cycling in bipolar type. Making Sense of Antiepileptic Drugs in 2007 Thomas K. Koch, MD Ortho McNeil Pharmaceuticals Speakers Bureau Abbott Laboratories Speakers Bureau Lamictal Dispersible - Summary of Product Characteristics (SmPC) by GlaxoSmithKline UK. Epilepsy. Adults and adolescents aged 13 years and above - Adjunctive or monotherapy treatment of partial seizures and generalised seizures, including tonic-clonic seizures. Non-Potassium-Sparing Diuretics The ECG changes and/or hypokalemia that may result from the administration of nonpotassium-sparing diuretics (such as loop or thiazide diuretics) can be lamictal prescriptions acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded.